There are also examples of longevity in isolated communities that have been investigated closely and an underlying genetic quirk of “inbreeding” that led to it (just like plenty of negatives).
Check out the discovery of ApoA-1Milano by researchers decades before the moniker Blue Zones was thunk up (I discovered that on that AbFab series “The Cholesterol Plays” by TMF poster edmiller back on the Foolish Collective board in Days of Yore). Or the discovery of the significance of the PCSK9 protein (and subsequent development of PCSK9 inhibitors) I first heard of this on Peter Attia’s site. It’s a shame that the old boards are inaccessible. I wonder if that was listed in edmiller’s list of things to keep an eye on for investment purposes.