Pharma companies selling online direct to patients…a direct threat to pharmacy benefit managers such as CVS.
There is a sweet spot for this. Even without insurance, generic drugs are deeply discounted by GoodRx and others. It’s the expensive on-patent drugs that are the sweet spot for direct sales from Big Pharma –> Patients, a win-win that cuts out the middlemen.
Drugmakers Are Ditching Middlemen to Sell Directly to Patients
Companies are rolling out direct-to-patient services, which are selling drugs for weight loss and other uses
By Peter Loftus, The Wall Street Journal, Dec. 8, 2025
- Drugmakers are increasingly selling medicines directly to patients, bypassing traditional middlemen and offering discounted prices, often half the list price.
- This direct-to-patient model is prominent in the weight-loss drug market, with Eli Lilly selling 30% of Zepbound prescriptions via its online service.
- Novo Nordisk sees 10% of its U.S. Wegovy prescription volume from direct cash purchases, contributing to an expected $11.9 billion in global sales. [end quote]
This doesn’t appear to have impacted CVS stock, probably because it’s only a tiny fraction of the overall market.
Wendy