I recently read about the university of Texas study where they fed identical15 gram meals to one group of 25 year olds and one group of 65 year olds. The younger group had robust results with their protein uptake and the older group had none. But when they doubled the dose, the younger group had no additional benefits and the the older group improved markedly. Later studies seem to confirm that seniors can synthesize proteins but they need larger doses.
Other studies have shown that seniors need to spread their consumption of protein throughout the day so now I try to get 30 grams of protein at both breakfast and dinner. Because I do not eat factory farmed meats for ethical/environmental reasons irrelevant to this conversation, I am eating more organic eggs and/or wild caught fish at the beginning and end of my eating window. Not sure I needed to share all this but I felt talkative.
Those all sound like good decisions to me. There is a lot of evidence now that the elderly need more protein than younger folks. This means that the concept of a âbalanced dietâ changes with age. We can probably be a bit more specific on what proteins to eat.
There are 20 amino acids used in humans. The body can generate 11 of these de novo. The nine amino acids it canât make are called the essential amino acids and these must come from diet (hopefully they all wonât be turned into glucose really fast as has been suggested!). Stands to reason that the focus should be to eat foods with lots of these amino acids.
Foods that contain all nine essential amino acids are called complete proteins. These foods include beef, poultry, fish, eggs, dairy, [soy], quinoa and buckwheat.
Foods that contain some but not all the essential amino acids are called incomplete proteins. These foods include nuts, seeds, beans and some grains. Amino Acid: Benefits & Food Sources
On a recent walking tour in the UK my favorite breakfast was kippers (smoked herring) with a poached egg and spinach. The Hollandaise sauce probably took a couple of days of my life span but it was a good start to the day.
I am a fan of intermittent fasting, though I do it intermittently. A couple of days a week I will have only a single meal (dinner) and eat whatever I want. Iâve found that to be the most sustainable pattern for me.
One thing to consider is that type 2 diabetes may have multiple causes. There has long been a link between inflammation and insulin resistance, though the exact biochemical pathway of how it occurs remains unclear.
Obesity is associated with low-level inflammation in a number of tissues/organs that include adipose tissues, muscles, kidney, liver, and pancreas. It wouldnât be much of a leap if a fat covered pancreas in a non-obese person is having its insulin-producing islet cells kill by fat-associated inflammation. https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.119.315896
My quick and superficial scan of the literature suggests that this is still mostly correlational although there are suggestive animal models indicating a causal link. If true then a low-inflammation diet may be useful. Foods that fight inflammation - Harvard Health
I have found 2-3 day bone broth fasts, still within my 8 hour eating window, also to be very beneficial FOR ME. Have gone as many as 4 days. Amazing the energy and well being I get from that. This is homemade bone broth, the type that is so gelatinous when cold that you spoon chunks out of the container, not liquid. Probably not all that low calorie, and with a bit of garlic and hot sauce it is stellar. Itâs my go-to when I am feeling stressed and out of control. Much healthier than that glass of wine, (which may help with the stress, temporarily, but not the control.)
Which is probably why modern medicine typically treats the symptoms, rather than address the root cause. The body is a chemically driven system. Put the right foods in, run the proper processes, (exercise,) and health is likely to be better than not.
IP
willing to make educated guesses and apply observations to determine changes needed
Today we all have pieces of truth in our comments and to varying degree along with individual needs.
Protein for seniors is a very big deal.
Those who are getting much olderâŚhopefully me as wellâŚneed their weight to be maintained at a reasonable level. There are some studies that say thin people are at a disadvantage to slightly heavier people. I am not talking overweight people.
At my age the focus for those of us who are overweight needs to be the toughest of all things cutting calorie. Ran into an friend two weeks ago who is type 1 diabetic. She has lost 80 pounds on Ozempic. She looks incredible. Her health is mightily improved. I was very happy for her.
I may consider it.
I also think with 10 plus years of use the scientists may find people can stop the drug and remain healthy. That might work for a modest percentage of the patients we will need to wait and see if that unfolds.
Hope she does not experience the nasty life threatening side effects that are being reported on the news. I would think 3 times about taking this drug.
I am not surprised. My dad taught me to be very conservative with any new drugs. This drugs is not new but the dosing is much higher.
I am reading on it nowâŚthe milder side effects disappear generally after two weeks. But they are often why people drop the drug.
Then there is this which I was shocked by with my friend. I did not understand her affect.
What does Ozempic do to your face?
âOzempic faceâ is a term for common side effects of the type 2 diabetes medication semaglutide (Ozempic). It can cause sagging and aging of facial skin. A doctor may recommend lifestyle modifications or facial fillers to treat these effects.
Honestly, the doctor at the end of the video report is being reckless. The .3% risk going to 1% is not a small thing. This seems to be across the board because the dosing is greater. When adding up 1% here and there over and over again we are talking over 5% very quickly.
Totally reckless.
I did warn my BIL. He was half kidding me to try Ozempic. I was serious it was too early to know as of last yearâs Christmas. He is not seeing people for obesity because he is head of the department but all of medicine has turned to this.
I am going nowhere near these two drugs. My risk profile is different than most people. What works is excellent. What does not work is really bad. I am not rolling the dice. In my case even though I am obese I have reversed out my problems with major weight loss. I am losing more weight nowâŚwith calorie restriction habits. Survival tactics.
I confess I didnât watch it. Was just providing you with a link. To have these results so early in the game is concerning. As more and more pile on with hopes of a pill that will lose weight for them, I can see things getting worse.
More than enough. I am my dadâs son. I wait out drug side effects to see if a drug stays on the market. I agree this will only get worse.
This can wipe out WW and Noom later with successful class action suits.
These side effects which are significant in numbers and are being ignored(worded better papered over with the FDA) by the pharma company will be financially damaging. But I do not know how much the law protects pharma corporations.
IndeedâŚand thanks for the link (took me till now to read, reread and think about it). I like these review articles as opposed to a Gish Gallop of links, cut ânâ paste snippets etc. for a good round up of info.
Mind you, I still think Prof Taylor (OP link) and his team did a bang up job of identifying one part of the mechanism leading to âdiabesityâ with their earlier studies. Namely, the role of ectopic fat in the pancreas in obese patients. More importantâŚthat reproducing the physical effects of bariatric surgery (sudden, massive drop in calories)âŚhad a similar beneficial effect on biomarkers together with a plausible mode of action to explain it (reduction in ectopic fat deposits). It was also reproducible. A possible part explanation of the âskinny fatâ/MO:NW phenom I mentioned upstream. All because someone thought âNow, thatâs pecularâŚâ and followed up on it. Probably did wonders for Optifast sales too.
Of course, this thread start concerned a study that reported a similar mode of action in the non obese. âNormal weightâ diabetics, in factâŚbut with poor body composition and, presumably, the same metabolic dysfunction at work âunder the hoodâ.
Anyone who purchased/waited for a library get of Peter Attiaâs âOutliveâ a few months back when @WendyBG (I think) mentioned it âŚand read it, of course âŚwill be somewhat up to speed on many of these individual topics. I fancy the prevailing mechanism for T2D secondary to metabolic syndrome was beta cell burnout prior to this, so a new puzzle piece on the table and support for the role of insulin resistance as an early trigger mechanism is a useful addition to the understanding.
All possible suspects on my check list of what might be responsible for that LDL-C of 135 or soâŚand all coming up short.
Yep. I realised that just over half a century ago (l Ionger if you count the time on my.mumâs watch) Been promoting the idea ⌠and more to the point practising the same ever since.
And thatâs the way it should be. There isnât a diet going that hasnât worked for some and failed for a heck of a lot more. Weâre all different in personal tastes, childhood experiences, susceptibility to peer pressure and slick marketing etcâŚand thatâs before any food so much as reaches the pie hole. Understanding a few fundamental principlesâŚmainly quality and quantityâŚallows most folk whoâre willing to be as accountable as needed to find something to tailor for their own needs. The See Food diet excepted, of courseâŚwhich I suspect is far more responsible for folk gaining weight and then maintaining it than itâs given credit forâŚhistorical revisionism/False Memory Syndrome notwithstanding!
Thinking back, now, to an era when âultra processed foodâ, âlow carb/low fatâ, âde novo lipogenisisâ (and the role of fructose) etc.etc.hadnât yet become buzz words for folk to thrash about. I recall convos with patients regarding the best way to put me out of business back when I was a newly minted general dentist, fresh out of my residency. Late 1970s. One question I would oftentimes ask about the cookie, candy, craptaculous diet they ate/allowed their kids to eat (even more import)âŚâIf the stuff youâre eating can wreak this havoc on your dentition, imagine what itâs doing to the rest of your/your childâs body.â No evidence that anyone did moving forward. Praise Be!!
Thatâs a platitude that isnât particularly helpful. What this thread illustrates is that what constitutes a âgood healthy dietâ is uncertain. This is what all the debate about all the different diets is all about. Fact is, nutrition science doesnât really have a good answer yet.
I know there are fans of Peter Attia on this board. He has long suggested that the traditional standard for a âbalanced dietâ, the Food Pyramid (or whatever it is called now), was/is a major contributor to the obesity epidemic. This is because it overemphasizes the consumption of carbohydrates.
For example, the current Dietary Guidelines for Americans (from the FDA) recommends that about 50% of daily calories come from carbs. This comes out for most people at about 250 grams of carbs/day. Carbohydrates: How carbs fit into a healthy diet - Mayo Clinic.
In comparison, a recent study showed that a low carb diet (about 60g/day) might significantly benefit individuals diagnosed as prediabetic. Since it is estimated that over 90 million Americans are prediabetic, a reduced carb diet could be the optimal one for a big chunk of the population.
In short, what constitutes a âhealthy balanced dietâ is largely in the eyes of the beholder.
I have met the enemy, and it is Carbs, at least for most Americans as a majority are overweight.
Yah but only when craptaculous diets are responsible for the dyslipidemia in the first place. Granted, itâs hard to fathom that not everyone chooses Bad Habits as a way of life given what we all see looking around, but such folk do exist.
I think I should start a populist movement to rival the HAES messageâŚhealth at every sizeâŚand call it Disease At Every Size. Meaning that even folk whoâre constantly good custodians on their bodies can get struck by diseases that have not been caused by poor lifestyle choices (the study subjects in the OP link might fall into this category but probably unlikely)
âŚwill be somewhat up to speed on many of these individual topics. I fancy the prevailing mechanism for T2D secondary to metabolic syndrome was beta cell burnout prior to this, so a new puzzle piece on the table and support for the role of insulin resistance as an early trigger mechanism is a useful addition to the understanding.
back when I was a newly minted general dentist, fresh out of my residency. Late 1970s. One question I would oftentimes ask about the cookie, candy, craptaculous diet they ate/allowed their kids to eat (even more import)âŚâIf the stuff youâre eating can wreak this havoc on your dentition, imagine what itâs doing to the rest of your/your childâs body.â No evidence that anyone did moving forward. Praise Be!!