Another theory… The actual physics of the “OEM provided” valve are quite impressive. There are a lot of factors involved in a valve that has to operate consistently 42 million times per year or about 3.7 billion times in a 90 year lifespan. It has to close almost completely to avoid back-flow, it has to open easily, and most importantly it has to GET OUT OF THE WAY when open to avoid imparting wierd turbulence and “eddies” in the flow of the fluid it is gating. That fluid has its own unique chemical properties that create flow behaviors far more complicated than normal fluids.
Any mal-formation of the “leaves” of that valve from the “factory-optimized design” can alter its effectiveness in closing or avoiding interference with the fluid being pumped. Since the blood being pumped has unique chemical factors for clotting, any change in flow that allows some blood to “stick” in an anomoly increases the chance of clotting or inflammation. That triggers other chemical responses in the body that can snowball, producing effects which worsen the problem (since they cannot correct the root problem which is a physical anomoly in the structure of the valve).
It makes some sense to me that abnormalities in the body’s processing of calcium could lead to deposits around the moving parts in the heart which would begin growing over time leading to accelerating deterioration of their functionality.
Once the heart’s pumping efficiency is impaired, it will pump HARDER to make up for the lost efficiency, that will enlarge the heart muscle, reduce the effective size of the chambers which will make the heart even LESS efficient, which will cause it to pump HARDER and the cycle will spiral. The harder the heart pumps, the higher the pressure on the aortic arch as the blood leaves the heart and any flaw in that area will get stressed, leading to aneurysms or narrowing from inflammation.
Caveat: I am not a doctor nor am I qualified to portray one on TV.
WTH