Cause of T2 Diabetes not what was expected

No idea exactly when, but I did read the Bowden book that was published in 2020. I don’t see anything this author is responding to that didn’t appear in the book. The title is still the same together with the implication that statin usage is worthless…so the same myths are prevailing

Not the take away I got, rather than it is over prescribed. I agree with that, as did DH’s cardiologist who replaced one that only looked at total cholesterol to prescribe statins.

1 Like

That is false. The relationship of fats in the bloodstream to insulin resistance is known. Carbs as in sugar are not the focus of insulin resistance. The glucose from the liver does not have to be from carbs. The blood fats are another matter. Fats, proteins, and carbs all become glucose and at very much the same rate in the liver. The false information in books that the timing of say a protein becoming glucose as slower is false. Proteins in your food become glucose very rapidly.

At the practical level this is the solution to the problem! Will power is not good enough, most of us just don’t have enough will power to overcome hunger pangs. A diet that eliminates hunger pangs is a large part of the solution. I love fruit for breakfast and they don’t eliminate hunger pangs but adding protein like eggs does seem to do the trick.

The Captain

1 Like

But there is no need for 8 billion diets. 100? 10?

The Captain

HA! So, you’ve made the same observation. Yes, some diets are good for some but not others. Others might be good for most. Three or four and maybe some therapeutic ones for people with unique medical conditions/allergies…?

According to doctors there is nothing I can safely eat. 100% lettuce all the time type stuff. But when I ask: Isn’t that an unbalanced diet? Crickets. And when I say I was a vegetarian for 25 yrs and still had the heart attack and BTW my triglycerides were over 1000 at times, all under doctors orders/recommendations, and no doctor seemed to have any comment. Crickets.

Another thing I notice. Whenever they want to make some claim about how well a new diet works (Or sometimes it’s an old diet a few people who live in the hills of some far away place have been eating for thousands of years) the comparison group is always overweight, crap eating couch potatoes with multiple afflictions. Well, d’uh, I think any reasonable diet would make you a metabolic and physiological Superman by comparison.

Know what actual Mediterraneans eat? Lots of refined starch. No “whole grains” except a dish or two here and there. Just like USA. Cured processed highly salted meat, cheese all the time and eggs. A lot of them. They do not eat any more fruits or vegetables than Americans eat. An apple here an orange there and some veg on the side at dinner. It’s all voodoo made-for-TV Madison avenue hope/fear mongering religion. Like the sign on the Springfield Dentist’s office says on The Simpsons: No matter how you’re brushing you’re doing it wrong. Eating seems to be the same way

2 Likes

Ah, well my experience was just the opposite…looking at my total cholesterol and mildly elevated LDL-C plus my excellent lifestyle choices over more than half a century, and high HDL over the past 15 years or so, my PCPs reassured me that statins were unnecessary…and who doesn’t want to hear that?

A bit of background reading, podcast listening etc led me to ask my new PCP if a bit more detailed testing (Lp(a) and Apo-b) plus a CAC scan might be in order (mainly to put my mind at rest). There were the culprits…elevated Lp (a) and Apo-b, the most atherogenic of the lipoprotein particles to date…and as a consequence found that I have 3 coronary arteries with greater than 80% stenosis.

Dr Jonny’s sidekick, Stephen Sinatra wouldn’t have prescribed statins either (he never prescribed them for women apparently…according to the book)

This is misleading. Carbs are the primary source of blood glucose. With respect to causing diabetes there are good and bad dietary carbs. Bad dietary carbs are the ones that get digested quickly and cause a rapid spike in blood glucose (e.g., donuts). Good carbs (e.g., fruits) are associated with lots of fiber and get digested slowly, producing more even blood glucose levels.

Dietary proteins and fats are generally only metabolized to glucose when starved for carbohydrates. However, bad dietary fats can inhibit muscle cells from responding to insulin to take up blood glucose. This is insulin resistance. Blood glucose levels go up, causing pancreatic insulin-producing cells to try to compensate. If they can’t, this is diabetes.

Dietary proteins do not increase blood glucose levels. Proteins are not how the body stores energy. It gets metabolized to glucose as a last resort.

8 Likes

A very on point observation in the context of the thread starter. Very low calorie diets have, as an inevitable side effect, a strong potential for significant muscle loss if caloric intake is way below total daily energy expenditure.

One reason I read the actual study so closely … I wanted to see if the study subjects had such a poor body composition (high %body fat at relatively normal weight) because they’d dieted down to their starting BMI in the first place.

It is true that surprisingly little is known with any certainty about nutrition. While I do think diet is important, I don’t think it is as critical as it is often made out to be. Afterall, obesity and diabetes weren’t a big problem in the 1950s and 1960s when Americans were eating Wonder Bread, TV dinners, and eating healthy was have a Jello fruit salad.

I think physical activity is much more important. The body is pretty good at getting what it needs from the stuff you eat. It just needs some help dealing with all the excess calories in the modern diet when life styles have become so sedentary. Nothing bad about eating a Twinkie while running a marathon as the body is in need of more quick energy. It’s the soda while watching TV that kills you.

This is particularly true for we older folk who are already tending to lose muscle. I think it is virtually impossible to eat too much protein if you are getting it from food (as opposed to supplements).

1 Like

You have heard that dozens of times it is not at all true. You can read that every day for the rest of your life in dozens of books. It still is not true.

Go talk to an endocrinologist. He will tell you it is garbage. Old garbage at that.

Not a word of truth in that. Totally false. Go talk to an endocrinologist. You know zero on the topic.

You are totally confused. Proteins do become glucose very rapidly when hitting the liver.

You have been reading crap for diet books. Total garbage.
+++++++++++++++
Where does protein get converted to glucose?

the liver

Protein is broken down into smaller substances called amino acids, which can help with muscle synthesis or be converted into glucose in the liver. Those amino acids stimulate gluconeogenesis, which is the generation of glucose from non-carbohydrate sources.Dec 29, 2021

My comment regardless of the terminology it is a very rapid immediate process. As we adults are not growing much almost all of it turns to glucose. Even in children most of it will turn to glucose depending on how much is eaten. If children have an abundance of proteins this is true.

My BIL an endocrinologist at BIDMC in Boston would say there is no real difference time-wise between sugars or carbs becoming glucose in the bloodstream and proteins entering the bloodstream as glucose. You’d be kidding yourself to think otherwise.

I totally get we are all miseducated over and over again on this topic. Stop paying for the books that lie to you.
++++++++++++

It is important for health reasons. Eat a small cheeseburger and your 300-calorie exercise walk is useless in that regard. Eat an avocado and it is worse. An avocado has more than 300 calories.

That is not so. The nutritionists do know a lot. Changing behaviors is tough. People tune into more radical ideas to push for change. These books generally avoid saying to eat fewer calories. That is too radical a change for most people. All of it turns to glucose in the liver at an extremely fast pace.

As far as older people eating more protein that is because one substance or chemical in protein helps retain the muscle you have. But if you have renal disease it is a very bad idea to eat more protein. Older people are much more prone to kidney disease.

I think your BIL would be mighty embarrased if he found out you were using him as a source for this misinformation. And if you are quoting him accurately, well…he deserves to be embarrassed

4 Likes

Do you know anything on the topic?

I am quoting him accurately. You are very misinformed for decades.

This quote is from Google. It debunks the garbage reading you and bt have been reading all your lives. You do not need to be embarrassed. People are wrong get over it.

According to BIl the process for carbs or proteins or fats time-wise is nothing. There are no timing differences.

VeeEnn you are over your head. You have been reading sheer garbage as we all have for decades.

Yeah, he had all those tested, triglycerides under 50, HDL over 50. No signs of inflammation. All numbers other than LDL and total cholesterol showed him to be in great shape. His first cardiologist had him overdosed on blood pressure meds as well, causing him to pass out more than once and having to wear a monitor for weeks at a time, which of course showed nothing. Worse yet, it took her office 5 days to respond to an emergency message. People, even doctors, are busy or lazy and just want an easy calculation of if total cholesterol > X, then statins.

Your experience proves the point that you need to be your own medical advocate.

IP

Well, if you read the @btresist comments you responded to…the ones you dismiss as garbage … you’ll see he’s talking about dietary sources of these macronutrients. That means from the diet and not from stored sources in the liver.

Even if you want to stick with that, glycogenolysis and gluconeogenesis are utilised primarily when carbohydrates are in short supply and glucose levels are low (pathology excepted, of course)

If your BIL needs further clarification (but I bet he doesn’t) he should scamper across the road to the Joslin Institute and have a chat with an endocrinologist there.

https://dtc.ucsf.edu/types-of-diabetes/type1/understanding-type-1-diabetes/how-the-body-processes-sugar/the-liver-blood-sugar/

Seems as though diabetes became a bigger problem after the Gov’t introduced the high grain oriented food pyramid, demonizing fats.

1 Like

That is not true at all. It is not a matter of in short supply. Almost all fat and protein are turned immediately by the liver into glucose.

Beth Israel Lahey Health is wrong. Protein is not second, fat is not third when consumed. It is all the same.

My BIL has nothing to do with the nutritionists. The nutritionists are not scientists. My BIL is a MD/Ph.D. Nutritionists are not as well educated or up to date particularly on how the liver operates.

Quoting nutritionists is lazy on your part.

The difference is the children and adults of the 1950s were born earlier.

The children and adults after 1960 on the diet have had more problems going into this period after 1995 or thereabout. It is on a rolling basis.

So, how come ketogenic diets work so well at producing ketones?

The reason any diet works is something is cut from the diet. As long as the cut calories are not compensated for somewhere else in the diet…the diet will work.

When you do the ketogenic diets and they work…they only work if you do not make it up in more protein calories as you adjust. You can gain weight on a ketogenic diet.