More OT pharmacology

Another gift from my pal Pete. This is one of his marketing emails that come on a Sunday so I’m pretty sure it’s not behind a paywall. I’m willing to bet this approval will be touted in the usual sources soon…if it hasn’t already hit the headlines. Anyways, a decent read…if only to give me reasonable confidence that it’s unlikely to be added to my treatment regimen. My hs-CRP has always been less than 1 for as long as it’s been measured …and is now around .2. Another confounder🤔

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Miraculously, the LoDoCo2 study linked in the article isn’t behind a paywall…

https://www.nejm.org/doi/full/10.1056/nejmoa2021372

A job for my husband when he’s done his other Sunday chores.

P.S…on a brief read through, I would’ve been well qualified for inclusion in this study. Yikes!!🫨

I’d recommend the rat poison first and foremost over this stuff.

https://www.mayoclinic.org/drugs-supplements/colchicine-oral-route/side-effects/drg-20067653?p=1

Why would that be, since Warfarin (aka “rat poison”) is an anti clotting agent with different indications for use than colchicine?

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I use rat poison figuratively. Might explain my tick.

:rofl: :rofl: :rofl:

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As in, a throwaway comment because you had nothing to say? Gottit!

Anyhoo, this is kind of interesting in a “new use for old drug…who knew” sorta way. Years ago…as in 2004/2005…there were a series of hugely popular and even more informative threads on the Foolish Collective board called The Cholesterol Plays from a poster edmiller. That was my first introduction to the idea of inflammation and measurement of hs-CRP as a strong predictor (allegedly) of cardiovascular events.

Because it was obviously an investment board, there was also a discussion of potential new drugs in the pipeline. A shame they’re no longer available to see what worked and what hasn’t

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I actually do have nothing much to say on this.

Except I wouldn’t which is why I said something.