OT New study of Organ Tissues

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{ Yahoo is using AI to generate takeaways from this article. This means the info may not always match what’s in the article. Reporting mistakes helps us improve the experience.

Key Takeaways

A new study has pinpointed age 50 as the turning point when human aging accelerates, with blood vessels being among the first tissues to show significant signs of decline.

Researchers analyzed proteins in various tissues from organ donors aged 14 to 68, finding that expressions of 48 disease-related proteins increased with age, with the most significant changes occurring between ages 45 and 55.

Injecting a protein associated with aging into young mice resulted in reduced physical performance, grip strength, endurance, balance, and coordination, highlighting the impact of aging on the body’s systems. }

Blood vessels. CVD n ASCVD, PVD, etc.
While these are certainly noteworthy conditions, MANY other tissues require adequate delivery of Nutrients O2 Water n heat… For proper functioning.

( Muscles for instance. See below for more…)

~48 disease related proteins, the concentration of “diseased proteins” reached a critical threshold between ages 45-50, at which point the consequences of malfunctioning proteins manifested a “disease”.

Injecting “old” proteins into young mice caused “old” symptoms.

This last one is similar to “heterochronic parabiosis” that was reported a couple years ago.

And lends some support to the concept of transfusing blood from a “young healthy” animal into an old-aged animal to “rejuvenate” the oldster.

Science RULES!
:eyes:
ralph

Or-
gan-
ism … Is a forbidden word.

The following is NOT medical advice.

Muscles, toes, etc require adequate blood flow … O2 delivery.
PVD interrupts blood flow - to the extremities, esp the lower legs n feet, toes.
Reduced blood flow causes painful tingling.

MANY people have painful lower leg n foot, toe tingling, and eventually numbness.

Medical “advice” says “oh, it’s diabetes, …” You’re gonna have to “accept it” and eventually, loose a couple toes, then a foot, then a lower leg… Etc.

But. If you can improve blood flow…
How? The muscles of the lower leg, CONTRACT, and put pressure on the VEINS, causing blood to move toward the heart.
Ie … Exercises: calf raises. Toe raises.

Also, massage - ie squeezing the muscles of the lower leg - puts pressure on the veins, causing blood to move toward the heart.
Lymphatic drainage massage, too.

If you wake up at 3am, with stinging, tingling lower legs n feet… Try doing some calf raises.

These exercises help move “low O2 blood” up toward the heart, allowing fresh, oxygenated blood to flow to the lower legs n feet, toes.

Since I’m NOT a DR… You need to Ask YOUR Dr if this is safe for you to do.

:chains:2
ralph

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What happens if you can’t lift the calf anymore because it is now a yearling?

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Brand it!
That’ll make it moove.

:scream:
ralph

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Now i bet andy is sorry

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A bit like the MailOnline, then?

Doesn’t reporting mistakes require the reader to actually be aware that they’re reading mistakes?

Asking for a friend…well, lots of 'em, really :face_with_hand_over_mouth:

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You can deduce what is wrong by asking questions from different points of view. But it takes time.

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Ralph,

How were these mistakes?

Aside from diabetes, were the statements mistakes?

I think it was Yahoo AI 'fessing up to the possible mistakes. I’m not sure Ralph would be aware or not since he threw a couple of caveats in there about checking with someone who might know.

Like I said, you’ve got to know enough to know AI might be wrong…and potentially even more to be able to ask the right questions to get a worthwhile answer.

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Like I’ve said you were trained as a dentist only.

Meanwhile Ralph was trained as a doctor.

@VeeEnn,

Ralph is not saying there are any mistakes in the article. He just cut and pasted the top disclaimer which could be on any Yahoo article.

You need to read more carefully, again.

The bolded parts by Ralph are “Key Takeaways” he wants to discuss. They are not mistakes.

If you would stop trying to talk down to people first, you’d read with a higher comprehension level.

Conversely, if you could read with a higher comprehension level, maybe you wouldn’t make the mistake of inferring I was talking down to people.

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You train like Milo of Croton, you continue to carry until it is a full grown bull.

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Bull you have a personal problem with this.

nuh uh! but, many classmates were on the Dr track. My undergrad was a small school that lumped us all together.

My education n work career is biology, chemistry, cell biology, cell physiology, n ecology.
I been around the edu-block.
:disguised_face:
ralph

I left the ‘header warning’ in the copy pasted info … cause it is just that… a caveat.

I didn’t see any ‘mistakes’ in the AI generated summary, that were obvious to me. It’s a rather general article.
I added my own comments … which might also include mistakes, especially since ‘disease’ can be ‘individual’ to the individual.
Take the ‘leg pain’ comments - if you have varicose veins, or ‘pooled blood’ for long periods. or some other condition that causes blood clots… then … SEE YOUR DR! blood clots are nothing to sneeze at.

:slight_smile: 2
ralph

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You see how much you learn by just asking questions? I have learned now that lifting calves might get you eaten by wolves. :laughing:

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wrt to the ‘caveat’ disclaimers … ALL AI’s are including some kind of ‘caveat’ that there may be ‘errors’ in the content produced by the AI LLM.
Due to the out cry about hallucinations or whatever.

This is EXACTLY similar to the ‘potential side effects’ warnings that accompany EVERY ‘drug, chemical’ that we get from a bottle or syringe.

Or, the ‘warning’ verbiage printed in the little 53page ‘book’ in 14 languages that accompanies EVERY device you purchase…

Cause ‘we’ are litigious and every company’s legal team says ‘put the warning there, cause somebody gone sue …’.

:mouse_trap: :kangaroo:
ralph

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I think also you get what you pay for. I have been using copilot, which is free, and have been asking it a lot of questions on bass boats. It has had many errors, but when I come back with a follow-up it acts like I am the genius for asking to have it reformulate it’s answer. :joy: But over all it does get to the right answer finally. I am sure the paid products are a lot better, at least that is what I hear.

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I use the FREE versions of Copilot, Gemini, Grok, ChatGPT, Perplexity, Claude, and now the ‘Yahoo AI summarizer thing’…
My ‘plan’ is to be ‘familiar’ with as many as possible, and perhaps eventually to maybe be able to get one to create an agentic that will actually do something useful… like bake a cake or drive the boat while I ski behind it.

or manipulate a GoPro on a drone Gimbel for taking pictures of my skin and input to the App for skin condition monitoring.

:locomotive:
ralph

Note the ‘caveats’…
ChatGPT says:
{ There are several apps designed to monitor moles and skin changes that could indicate skin cancer. These apps typically allow users to take photos of moles, track changes over time, and sometimes use AI to assess risk. However, none of them replace a professional dermatologist’s evaluation. Here are some of the most well-known:

1. Miiskin

  • Features: Mole tracking with photo comparison, face and body mapping, automatic reminders.
  • AI?: Does not diagnose but helps document changes.
  • Platform: iOS and Android.
  • Trusted?: CE-marked in Europe, often recommended by dermatologists for tracking.

2. SkinVision

  • Features: Uses AI to assess photos of skin spots for cancer risk.
  • AI?: Yes – provides a risk rating (low, medium, high).
  • Platform: iOS and Android.
  • Trusted?: CE-certified, clinically tested; not FDA-approved in the U.S.
  • Cost: Paid version required for AI analysis.

3. MoleScope

  • Features: Works with a special device to take high-resolution mole images; integrates with dermatology services.
  • AI?: Not directly – more for professional use.
  • Platform: iOS and Android.
  • Trusted?: Developed by MetaOptima, used in teledermatology.

4. Dermatology-focused Telehealth Apps (e.g., Teladoc, First Derm)

  • Features: Let you send images directly to licensed dermatologists for analysis.
  • AI?: No – real dermatologists review your case.
  • Cost: Typically pay-per-use.

:warning: Important Note:

Apps that claim to diagnose skin cancer using AI should be approached cautiously unless they’re certified by health authorities. The FDA has not approved any consumer app for skin cancer diagnosis as of now.

For accurate diagnosis, suspicious moles or spots should always be checked by a board-certified dermatologist. These apps can be helpful for early detection and tracking, not final diagnosis. }

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Wow, I didn’t even know they had that available.

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